We study the inclusive (y,¯ p) and (p,p) reactions in nuclei and check the sensitivity to the¯p annihilation mechanisms. We find that including the many body annihilation mechanisms in nuclei reduces appreciably the cross section of these reactions with respect to the evaluation considering only the one body mechanism of¯p annihilation. This shows that the¯p production reactions are more sensitive to¯p annihilation than the direct¯p annihilation reactions and makes the production experiments very useful tools to investigate the complex mechanisms of¯p annihilation in nuclei.