The use of plutonium in the fuel cycle during complex utilization of thermal and fast reactors in nuclear energetics permits solving the problem of ensuring nuclear fuel for a long period. Oxide uranium-plutonium fuel facilitates the development of technology of fast reactors and so far it is considered as the basic type of fuel. At the same time, oxide fuel cannot ensure the required rate of plutonium accumulation, in view of which the investigations of more efficient fuel and constructional materials become a pressing problem. The use of uranium-plutonium oxide fuel in thermal reactors requires improvements in the construction of fuel elements and organization of large-scale completely automatic production.