Limits of warm and cold stress in different climatic regions are determined by means of temperature, wind speed and humidity for the period 1976-1985. These values are measured at 2 PM local time during July for warm stress and at 7 AM local time during January for cold stress. Hvar (20 m ASL) is used to represent maritime climate, Zavižan on the top of Mount Velebit (1594 m ASL) and Skrad (668 m ASL) in Gorski Kotar are represetatives of mountainous climate, and Zagreb (128 m ASL) is representative of continental lowland climate. Values of a biometeorological Temperature-Wind Speed-Humidity TWH-index higher than the 98% value of theoretical distribution fitted to empirical data represent above normal extreme conditions at a given location, and TWH values less than 2% value of the theoretical distribution represent below normal extreme conditions. For similar temperatures, it will be extremaly above normal at the top of Mount Velebit (Zavižan) whilst normal on the coast (Hvar), and similarly, it will be extremely below normal in Hvar but normal at Zavižan.