Adolescent drug abuse is one of the nations' leading social problems. Secondary intervention programs have rarely designed treatments to address specific issues pertinent to the black adolescent drug user. Among these special issues is cultural sensitivity in clinical practice and research. A review of the research literature revealed no empirical work that has been conducted in the area of cultural sensitivity as it relates to black male adolescent substance abusers. The author proposes methodological considerations as applied to four phases of treatment: assessment, planning intervention, implementation, and termination and gives suggestions for how culturally sensitive therapeutic intervention can be conducted with chemically dependent adolescent black males.