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image/svg+xml Jakob Voss, based on art designer at PLoS, modified by Wikipedia users Nina and Beao Closed Access logo, derived from PLoS Open Access logo. This version with transparent background. http://commons.wikimedia.org/wiki/File:Closed_Access_logo_transparent.svg Jakob Voss, based on art designer at PLoS, modified by Wikipedia users Nina and Beao Psychopharmacologyarrow_drop_down
image/svg+xml Jakob Voss, based on art designer at PLoS, modified by Wikipedia users Nina and Beao Closed Access logo, derived from PLoS Open Access logo. This version with transparent background. http://commons.wikimedia.org/wiki/File:Closed_Access_logo_transparent.svg Jakob Voss, based on art designer at PLoS, modified by Wikipedia users Nina and Beao
Psychopharmacology
Article . 1974 . Peer-reviewed
License: Springer TDM
Data sources: Crossref
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The effect of some cholinolytic drugs on a number of behavioural parameters measured in the T-maze alternation test: Dose-response relationships

Authors: A.M. van der Poel;

The effect of some cholinolytic drugs on a number of behavioural parameters measured in the T-maze alternation test: Dose-response relationships

Abstract

Conflict behaviour in a T-maze can be observed at the choice point, involving simultaneous tendencies to move left and right and in the goal box involving simultaneous tendencies to approach the reward and to return towards the choice point. Firstly, the effects of different doses (from 0.06 to 1 mg/kg) of the cholinolytic drug 3-quinuclidinyl benzilate on the alternation of choice directions and on the choice point conflict were studied. Secondly, the goal box conflict was studied following administration of different doses (0.03 to 1 mg/kg) of another cholinolytic drug N-methyl-4-piperidyl methylethynyl-glycolate. It was observed that the suppression of alternation to chance levels developed at similar dose levels as the intensification of the conflict behaviour. The present observations are in agreement with a previous dose-response study of 3-quinuclidinyl benzilate and behavioural conflict in a circular runway.

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Keywords

Quinuclidines, Time Factors, Behavior, Animal, Dose-Response Relationship, Drug, Parasympatholytics, Rats, Inbred Strains, Cyclopentanes, Drug Tolerance, Benzilates, Glycolates, Rats, Conflict, Psychological, Piperidines, Animals, Female, Injections, Intraperitoneal

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citations
This is an alternative to the "Influence" indicator, which also reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
BIP!Citations provided by BIP!
popularity
This indicator reflects the "current" impact/attention (the "hype") of an article in the research community at large, based on the underlying citation network.
BIP!Popularity provided by BIP!
influence
This indicator reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
BIP!Influence provided by BIP!
impulse
This indicator reflects the initial momentum of an article directly after its publication, based on the underlying citation network.
BIP!Impulse provided by BIP!
5
Average
Average
Average
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