The synthesis of S-adenosylmethionine by mutants with defects in S-adenosylmethionine synthetase

descriptionPublicationkeyboard_double_arrow_right Article 01 Jan 1976 English Publisher:Springer Science and Business Media LLCJournal:Molecular and General Genetics MGG, volume 144, pages 87-95 (issn: 0026-8925, eissn: 1432-1874,

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Authors: A C, Hobson;

doi: 10.1007/bf00277310

pmid: 772417

The synthesis of S-adenosylmethionine by mutants with defects in S-adenosylmethionine synthetase

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Abstract

Some metK mutants of Salmonella typhimurium with constitutive methionine biosynthesis have no detectable S-adenosylmethionine (SAM) synthetase, the enzyme which converts methionine to SAM, the postulated corepressor of the methionine pathway. However, these mutants are not auxotrophic for SAM, an essential compound for many reactions.

Related Organizations

University of Birmingham
United Kingdom

Keywords

Salmonella typhimurium, S-Adenosylmethionine, Genes, Transduction, Genetic, Transferases, Mutation, Methionine Adenosyltransferase, Enzyme Repression, Salmonella Phages

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