Microbial contamination of radionuclide generators

descriptionPublicationkeyboard_double_arrow_right Article 01 Jan 1977 English Publisher:Springer Science and Business Media LLCJournal:European Journal of Nuclear Medicine, volume 2 (issn: 0340-6997, eissn: 1619-7089,

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Authors: K, Sorensen; K, Kristensen; P, Frandsen;

doi: 10.1007/bf00253681

pmid: 891554

Microbial contamination of radionuclide generators

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Abstract

Technetium-99m generators were grossly contaminted using 5 different strains of microorganisms. Elution of the generators showed that the number of microorganisms was reduced by a factor of 10(4)-10(6). There were no indications that the generators would support bacterial growth. It is concluded that it would be acceptable from a microbiologic point of view to omit autoclaving and membrane filtration of the final product provided that proper aseptic techniques are applied.

Related Organizations

National Health Service
United Kingdom

Keywords

Quality Control, Radioisotopes, Bacteria, Technetium, Nuclear Medicine, Decontamination

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