According to their chemical composition, rich in volatile compounds, comets are thought to be primitive materials. They may provide prime samples for the study of nucleosynthetic components of the solar system and of the processes occurring during the formation of the outer planets. Their origin is largely a matter of conjecture. Chromium isotopic measurements in carbonaceous chondrites illustrate how the non-volatile part of cometary material can be investigated both for isotopic heterogeneity and for the extinct nuclide 53Mn. Questions like the possible presence of 26Al as a heat source can also be addressed by these measurements.