Intramedullary bone formation after polylactic acid wire implantation

descriptionPublicationkeyboard_double_arrow_right Article 01 Jan 1994 English Publisher:Springer Science and Business Media LLCJournal:Journal of Materials Science: Materials in Medicine, volume 5, pages 407-410 (issn: 0957-4530, eissn: 1573-4838,

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Authors: T. E. Otto; P. Patka; H. J. Th. M. Haarman; C. P. A. T. Klein; R. Vriesde;

doi: 10.1007/bf00058974

Intramedullary bone formation after polylactic acid wire implantation

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Abstract

Semi-crystalline poly-L-lactic acid (PLLA) wire was implanted intramedullary in rat tibiae to evaluate the fracture healing processes and the tissue reaction on the PLLA in a fractured bone. The fracture healing after PLLA implantation was compared to a sham-operated group of animals. In all animals with intramedullary PLLA wire implantation newly formed bone was seen immediately against the implant 2 and 6 months after implantation. None of the shamoperated animals showed newly formed intramedullary bone formation other than fracture healing callus and normal trabecular bone.

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