descriptionPublicationkeyboard_double_arrow_right Part of book or chapter of book , Article , Other literature type 01 Jan 2002Publisher:Birkhäuser Basel

Authors: Gonzalo, Giribet; Ward C, Wheeler; Jyrki, Muona;

doi: 10.1007/978-3-0348-8114-2_7

pmid: 11924489

DNA multiple sequence alignments

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Abstract

In this chapter we examine the procedure of multiple sequence alignment. We first examine the heuristic procedures commonly used in multiple sequence alignment. Next we examine sources of ambiguity involved in the alignment procedure. We suggest that several alignment parameters be employed to examine alignment sensitivity. We end by presenting an experiment with humans showing the ambiguity involved in manual alignment.

Related Organizations

American Museum of Natural History
United States
University of Helsinki
Finland
Harvard University
United States
Finnish Museum of Natural History
Finland

Keywords

Sequence Homology, Nucleic Acid, Humans, Sequence Analysis, DNA, Sequence Alignment

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