Segregation occurs when individuals who identify, or are identified, with different groups occupy different geographies within cities. Although segregation can be seen as a continuum from dispersion through extreme cases exemplified by ghettos, it remains a persistent feature of cities across the globe. Immigration features prominently in segregation and reflects a range of factors including discrimination and racism, housing, labor market access, and economic opportunities. Focusing on the immigration perspective, the following chapter explores the urban geography of segregation, including its definition, causes and patterns, methods for detecting and understanding segregation, and implications of segregation.