Graves’ disease was first described by Caleb H. Parry in 1825. The first case among his 6 patients seen in 1786 had experienced palpitation, neck swelling and protrusion of eyes after delivery(1). Thus the first patients with Graves’ (Parry’s) disease described in the medical literature was of postpartum onset. In 1840, Karl A. von Basedow reported 4 cases of Graves’ (Basedow’s) disease(2). Interestingly, one of his 3 female patients was also a case of postpartum onset. Reviewing these old reports, it is likely that postpartum onset of Graves’ disease may be frequently observed in the general population. However, little is known about the mechanism of postpartum onset of Graves’ disease.