Phylogenetic analysis of porcine circovirus 3 circulating in Canadian pigs
Copyright policy )Phylogenetic analysis of porcine circovirus 3 circulating in Canadian pigs
Abstract Introduction Porcine circovirus 3 (PCV3) has been detected in pigs worldwide and associated with several clinical signs. Methods To investigate the genetic diversity of PCV3 strains circulating in Canada, 44 PCV3 positive samples from Saskatchewan (2/44), Manitoba (2/44), Quebec (4/44), Alberta (11/44) and Ontario (25/44) submitted to diagnostic laboratories in Canada between 2019 and 2021 were sequenced and analyzed. Results Phylogenetic analysis of capsid genes showed that all of the 44 Canadian strains classified into PCV3a and segregated into seven lineages with common amino acid changes observed at A24V, R27K, N56D, T77S, Q98R, L150I (F) and R168K positions. Conclusion Future studies are required to determine whether the polymorphisms in capsid proteins, as revealed in this study, could be associated with differences in the pathogenicity or antigenicity of PCV3 strains. This is the first phylogenetic analysis of PCV3 strains among different provinces in Canada.
- University of Montreal Canada
- University of Guelph Canada
- Simon Fraser University Canada
- University of Saskatchewan Canada
Circovirus, Swine Diseases, Canada, Phylogenetic analysis, Swine, phylogenetic analysis, Veterinary medicine, Canadian pigs, SF600-1100, porcine circovirus 3, Animals, PIGS, Capsid Proteins, Porcine circovirus 3, Amino Acids, Circoviridae Infections, Phylogeny
Circovirus, Swine Diseases, Canada, Phylogenetic analysis, Swine, phylogenetic analysis, Veterinary medicine, Canadian pigs, SF600-1100, porcine circovirus 3, Animals, PIGS, Capsid Proteins, Porcine circovirus 3, Amino Acids, Circoviridae Infections, Phylogeny
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