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image/svg+xml Jakob Voss, based on art designer at PLoS, modified by Wikipedia users Nina and Beao Closed Access logo, derived from PLoS Open Access logo. This version with transparent background. http://commons.wikimedia.org/wiki/File:Closed_Access_logo_transparent.svg Jakob Voss, based on art designer at PLoS, modified by Wikipedia users Nina and Beao Statistics in Medici...arrow_drop_down
image/svg+xml Jakob Voss, based on art designer at PLoS, modified by Wikipedia users Nina and Beao Closed Access logo, derived from PLoS Open Access logo. This version with transparent background. http://commons.wikimedia.org/wiki/File:Closed_Access_logo_transparent.svg Jakob Voss, based on art designer at PLoS, modified by Wikipedia users Nina and Beao
Statistics in Medicine
Article . 2020 . Peer-reviewed
License: Wiley Online Library User Agreement
Data sources: Crossref
image/svg+xml Jakob Voss, based on art designer at PLoS, modified by Wikipedia users Nina and Beao Closed Access logo, derived from PLoS Open Access logo. This version with transparent background. http://commons.wikimedia.org/wiki/File:Closed_Access_logo_transparent.svg Jakob Voss, based on art designer at PLoS, modified by Wikipedia users Nina and Beao
zbMATH Open
Article . 2021
Data sources: zbMATH Open
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Robust Wald‐type tests under random censoring

Robust Wald-type tests under random censoring
Authors: Abhik Ghosh; Ayanendranath Basu; Leandro Pardo;

Robust Wald‐type tests under random censoring

Abstract

Randomly censored survival data are frequently encountered in biomedical or reliability applications and clinical trial analyses. Testing the significance of statistical hypotheses is crucial in such analyses to get conclusive inference but the existing likelihood‐based tests, under a fully parametric model, are extremely nonrobust against outliers in the data. Although there exists a few robust estimators given randomly censored data, there is hardly any robust testing procedure available in the literature in this context. One of the major difficulties here is the construction of a suitable consistent estimator of the asymptotic variance of robust estimators, since the latter is a function of the unknown censoring distribution. In this article, we take the first step in this direction by proposing a consistent estimator of asymptotic variance of the M‐estimators based on randomly censored data without any assumption on the censoring scheme. We then describe and study a class of robust Wald‐type tests for parametric statistical hypothesis, both simple as well as composite, under such a set‐up. Robust tests for comparing two independent randomly censored samples and robust tests against one sided alternatives are also discussed. Their advantages and usefulness are demonstrated for the tests based on the minimum density power divergence estimators and illustrated with clinical trials and other medical data.

Keywords

random censored data, Likelihood Functions, Models, Statistical, Reproducibility of Results, M-estimator, informative censoring, Applications of statistics to biology and medical sciences; meta analysis, Data Interpretation, Statistical, clinical trial analysis, Humans, minimum density power divergence estimator, robust hypothesis testing

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selected citations
These citations are derived from selected sources.
This is an alternative to the "Influence" indicator, which also reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
BIP!Citations provided by BIP!
popularity
This indicator reflects the "current" impact/attention (the "hype") of an article in the research community at large, based on the underlying citation network.
BIP!Popularity provided by BIP!
influence
This indicator reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
BIP!Influence provided by BIP!
impulse
This indicator reflects the initial momentum of an article directly after its publication, based on the underlying citation network.
BIP!Impulse provided by BIP!
9
Top 10%
Average
Top 10%
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