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Statistics in Medicine
Article . 2017 . Peer-reviewed
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Article . 2017
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https://dx.doi.org/10.48550/ar...
Article . 2017
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Survival trees for interval‐censored survival data

Survival trees for interval-censored survival data
Authors: Wei Fu; Jeffrey S. Simonoff;

Survival trees for interval‐censored survival data

Abstract

Interval‐censored data, in which the event time is only known to lie in some time interval, arise commonly in practice, for example, in a medical study in which patients visit clinics or hospitals at prescheduled times and the events of interest occur between visits. Such data are appropriately analyzed using methods that account for this uncertainty in event time measurement. In this paper, we propose a survival tree method for interval‐censored data based on the conditional inference framework. Using Monte Carlo simulations, we find that the tree is effective in uncovering underlying tree structure, performs similarly to an interval‐censored Cox proportional hazards model fit when the true relationship is linear, and performs at least as well as (and in the presence of right‐censoring outperforms) the Cox model when the true relationship is not linear. Further, the interval‐censored tree outperforms survival trees based on imputing the event time as an endpoint or the midpoint of the censoring interval. We illustrate the application of the method on tooth emergence data.

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Keywords

Male, FOS: Computer and information sciences, Oral Health, Biostatistics, interval-censored data, survival tree, Survival Analysis, Statistics, Nonparametric, Applications of statistics to biology and medical sciences; meta analysis, Tooth Eruption, Methodology (stat.ME), Child, Preschool, conditional inference tree, Humans, Computer Simulation, Child, Monte Carlo Method, Statistics - Methodology, Algorithms, Proportional Hazards Models

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    selected citations
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    This is an alternative to the "Influence" indicator, which also reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
    19
    popularity
    This indicator reflects the "current" impact/attention (the "hype") of an article in the research community at large, based on the underlying citation network.
    Top 10%
    influence
    This indicator reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
    Top 10%
    impulse
    This indicator reflects the initial momentum of an article directly after its publication, based on the underlying citation network.
    Top 10%
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selected citations
These citations are derived from selected sources.
This is an alternative to the "Influence" indicator, which also reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
BIP!Citations provided by BIP!
popularity
This indicator reflects the "current" impact/attention (the "hype") of an article in the research community at large, based on the underlying citation network.
BIP!Popularity provided by BIP!
influence
This indicator reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
BIP!Influence provided by BIP!
impulse
This indicator reflects the initial momentum of an article directly after its publication, based on the underlying citation network.
BIP!Impulse provided by BIP!
19
Top 10%
Top 10%
Top 10%
Green
bronze