Clinical risk reclassification at 10 years
Copyright policy )Clinical risk reclassification at 10 years
Three papers in this issue focus on the role of calibration in model fit statistics, including the net reclassification improvement (NRI) and integrated discrimination improvement (IDI). This commentary reviews the development of such reclassification statistics along with more recent advances in our understanding of these measures. We show how the two‐category NRI and the IDI are affected by changes in the event rate in theory and in an applied example. We also describe the role of calibration and how it may be assessed. Finally, we discuss the relevance of the event rate NRI for clinical use. Copyright © 2017 John Wiley & Sons, Ltd.
- Brigham and Women's Faulkner Hospital United States
- Harvard University United States
Male, Biometry, reclassification, clinical utility, calibration, Risk Assessment, Applications of statistics to biology and medical sciences; meta analysis, Cardiovascular Diseases, Risk Factors, Area Under Curve, Calibration, Humans, Computer Simulation, Female, Biomarkers
Male, Biometry, reclassification, clinical utility, calibration, Risk Assessment, Applications of statistics to biology and medical sciences; meta analysis, Cardiovascular Diseases, Risk Factors, Area Under Curve, Calibration, Humans, Computer Simulation, Female, Biomarkers
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