
doi: 10.1002/sim.719
pmid: 11304740
AbstractInterval‐censored survival data often occur in medical studies, especially in clinical trials. In this case, many authors have considered estimation of a survival function. There is, however, relatively little discussion on estimating the variance of estimated survival functions. For right‐censored data, a special case of interval‐censored data, the most commonly used method for variance estimation is to use the Greenwood formula. In this paper we propose a generalization of the Greenwood formula for variance estimation of a survival function based on interval‐censored data. Also a simple bootstrap approach is presented. The two methods are evaluated and compared using simulation studies and a real data set. The simulation results suggest that the methods work well. Copyright © 2001 John Wiley & Sons, Ltd.
Analysis of Variance, Clinical Trials as Topic, Likelihood Functions, Data Interpretation, Statistical, Humans, Breast Neoplasms, Female, Survival Analysis
Analysis of Variance, Clinical Trials as Topic, Likelihood Functions, Data Interpretation, Statistical, Humans, Breast Neoplasms, Female, Survival Analysis
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