Antiprotozoal activity of Neurolaena lobata
Copyright policy )Antiprotozoal activity of Neurolaena lobata
AbstractExtracts, fractions and sesquiterpene lactones from Neurolaena lobata (L.) R. Br. (Asteraceae), a traditional medicinal plant from Guatemala, were tested in vitro against Leishmania spp. promastigotes, Trypanosoma cruzi trypomastigotes and epimastigotes and Trichomonas vaginalis trophozoites. The ethanol extract inhibited the parasite growth of L. mexicana, T. cruzi and T. vaginalis significantly. The pure germacranolides 1 and a mixture of 2 and 3, isolated from the ethonal extract, were highly active against L. mexicana and T. cruzi. Copyright © 2001 John Wiley & Sons, Ltd.
- University of Vienna Austria
- Heinrich Heine University Düsseldorf Germany
- University of San Carlos of Guatemala Guatemala
- University of Duesseldorf Germany
Pharmacology, Leishmania, Pharmakologie, Plants, Medicinal, Plant Extracts, Trypanosoma cruzi, Antiprotozoal Agents, Eukaryota, Asteraceae, Toxicology, Plant Leaves, Parasitic Sensitivity Tests, Toxikologie, 3012 Pharmacy, Trichomonas vaginalis, Animals, Humans, 3012 Pharmazie
Pharmacology, Leishmania, Pharmakologie, Plants, Medicinal, Plant Extracts, Trypanosoma cruzi, Antiprotozoal Agents, Eukaryota, Asteraceae, Toxicology, Plant Leaves, Parasitic Sensitivity Tests, Toxikologie, 3012 Pharmacy, Trichomonas vaginalis, Animals, Humans, 3012 Pharmazie
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