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Proteins Structure Function and Bioinformatics
Article . 2011 . Peer-reviewed
License: Wiley Online Library User Agreement
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Evaluation of residue–residue contact predictions in CASP9

Authors: Bohdan Monastyrskyy; Krzysztof Fidelis; TRAMONTANO, ANNA; Andriy Kryshtafovych;

Evaluation of residue–residue contact predictions in CASP9

Abstract

AbstractThis work presents the results of the assessment of the intramolecular residue–residue contact predictions submitted to CASP9. The methodology for the assessment does not differ from that used in previous CASPs, with two basic evaluation measures being the precision in recognizing contacts and the difference between the distribution of distances in the subset of predicted contact pairs versus all pairs of residues in the structure. The emphasis is placed on the prediction of long‐range contacts (i.e., contacts between residues separated by at least 24 residues along sequence) in target proteins that cannot be easily modeled by homology. Although there is considerable activity in the field, the current analysis reports no discernable progress since CASP8. Proteins 2011; © 2011 Wiley‐Liss, Inc.

Countries
Saudi Arabia, Italy
Keywords

Models, Molecular, Residue-residue contact prediction, Protein Conformation, Intramolecular contacts, Molecular, Computational Biology, Proteins, casp; intramolecular contacts; protein structure modeling; residue-residue contact prediction, Models, CASP, Protein structure modeling, Software

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    influence
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selected citations
These citations are derived from selected sources.
This is an alternative to the "Influence" indicator, which also reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
BIP!Citations provided by BIP!
popularity
This indicator reflects the "current" impact/attention (the "hype") of an article in the research community at large, based on the underlying citation network.
BIP!Popularity provided by BIP!
influence
This indicator reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
BIP!Influence provided by BIP!
impulse
This indicator reflects the initial momentum of an article directly after its publication, based on the underlying citation network.
BIP!Impulse provided by BIP!
52
Top 10%
Top 10%
Top 10%
bronze