Key pointsWhat is already known about this topic? Single‐site studies suggest racial, ethnic, and insurance disparities in use of Non‐invasive prenatal testing (NIPT). Population‐level research from outside the U.S. highlights significant geographic variations in NIPT uptake. What does this study add? Enrollees living in zip‐codes with a higher proportion of Black and Hispanic/Latino residents were significantly less likely to receive NIPT. Enrollees living in zip‐codes with a higher proportion of people living below the federal poverty level (FPL) were significantly less likely to receive NIPT. Birthing people with Medicaid were five times less likely to receive NIPT than those with commercial coverage.