Language impairment in cerebellar ataxia
Copyright policy )Language impairment in cerebellar ataxia
ABSTRACTBackgroundSeveral studies have suggested that language impairment can be observed in patients with cerebellar pathology. The aim of this study was to investigate language performance in patients with spinocerebellar ataxia type 6 (SCA6).MethodsWe assessed speech and language in 29 SCA6 patients with standardized linquistic tests and correlated this with the severity of ataxia, as quantified by the Scale of Assessment and Rating of Ataxia.ResultsIndividual patients show mild‐to‐moderate linguistic impairment. Linguistic abnormalities were most distinct on the writing and comprehension subtests. A strong correlation between severity of ataxia and linguistic performance was consistently found.ConclusionsThis study confirms the occurrence of linguistic impairments in patients with cerebellar degenerative diseases, such as SCA6. The relation between linguistic abnormalities and severity of ataxia provides further evidence for a role of the cerebellum in linguistic processing. © 2014 International Parkinson and Movement Disorder Society
- University Medical Center Groningen Netherlands
- Radboud University Nijmegen Netherlands
- University of Groningen Netherlands
- Radboud University Nijmegen Medical Centre Netherlands
Male, Cerebellar Ataxia, CHILDREN, COGNITIVE-AFFECTIVE SYNDROME, Neuropsychological Tests, Severity of Illness Index, Radboudumc 3: Disorders of movement RIHS: Radboud Institute for Health Sciences, Calcium Channels, N-Type, ADOLESCENTS, Humans, Aged, DAMAGE, Aged, 80 and over, Language Disorders, LESIONS, language impairment, Radboudumc 3: Disorders of movement DCMN: Donders Center for Medical Neuroscience, DEGENERATION, Middle Aged, aphasia, NEGLECT, Female, cerebellar ataxia, VERB GENERATION, APHASIA, Calcium Channels, MOTOR, Cognition Disorders
Male, Cerebellar Ataxia, CHILDREN, COGNITIVE-AFFECTIVE SYNDROME, Neuropsychological Tests, Severity of Illness Index, Radboudumc 3: Disorders of movement RIHS: Radboud Institute for Health Sciences, Calcium Channels, N-Type, ADOLESCENTS, Humans, Aged, DAMAGE, Aged, 80 and over, Language Disorders, LESIONS, language impairment, Radboudumc 3: Disorders of movement DCMN: Donders Center for Medical Neuroscience, DEGENERATION, Middle Aged, aphasia, NEGLECT, Female, cerebellar ataxia, VERB GENERATION, APHASIA, Calcium Channels, MOTOR, Cognition Disorders
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