Kinetics of Degradation of Biapenem

descriptionPublicationkeyboard_double_arrow_right Article 03 Jun 2014 English Publisher:WileyJournal:International Journal of Chemical Kinetics, volume 46, pages 443-450 (issn: 0538-8066, eissn: 1097-4601,

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Authors: JUDYTA CIELECKA‐PIONTEK; PRZEMYSŁAW ZALEWSKI; PIOTR GARBACKI; EWELINA JURA; ALICJA TALACZYŃSKA;

doi: 10.1002/kin.20860

Kinetics of Degradation of Biapenem

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Abstract

ABSTRACTThe kinetic and thermodynamic analysis of biapenem degradation was conducted during acid–base hydrolysis, under the influence of buffer components and in the solid state at increased temperature (dry air) and relative air humidity (RH > 50%). The effects of the initial concentration of biapenem and the formation of degradation products on its stability were investigated.

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Poznan University of Medical Sciences
Poland

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