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Toxoplasma Antibodies and Spontaneous Abortion

descriptionPublicationkeyboard_double_arrow_right Article 01 Jul 1978 Greece English Publisher:WileyJournal:International Journal of Gynecology & Obstetrics, volume 15, pages 299-301 (issn: 0020-7292, eissn: 1879-3479,

Authors: Lolis, D.; Tzigounis, V.; Michalas, S.; Koumentakou, E.; Kaskarelis, D.;

doi: 10.1002/j.1879-3479.1977.tb00697.x

pmid: 25801

Toxoplasma Antibodies and Spontaneous Abortion

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Abstract

ABSTRACTOne hundred and fifty‐two women with spontaneous abortion were investigated by hemagglutination (HA) and immunofluorescence antibody (IFA) tests for toxoplasmosis. In 48 cases, quantitive immunoglobulin (Ig) studies and mouse inoculation with gestational material were performed. Positive toxoplasma antibody titers were observed in 62 cases (40.8%) using HA and in 52 cases (38.2%) using IFA. This prevalence was significantly higher than that observed in 80 normal women who served as controls. Toxoplasma gondii was isolated in two cases. No correlation was found between antibody titers and IgG, IgM or IgA levels. We conclude that toxoplasmosis should be considered as the cause of abortion when a patient's antibody titer exceeds 1:256.

Country

Greece

Related Organizations

National and Kapodistrian University of Athens
Greece

Keywords

Abortion, Spontaneous, Pregnancy, Fluorescent Antibody Technique, Humans, Immunoglobulins, Female, Hemagglutination Tests, Pregnancy Complications, Infectious, Antibodies, Toxoplasmosis

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