Withanolides from Withania adpressa

descriptionPublicationkeyboard_double_arrow_right Article 01 Feb 2007 Switzerland English Publisher:WileyJournal:Helvetica Chimica Acta, volume 90, pages 346-352 (issn: 0018-019X, eissn: 1522-2675,

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Authors: Abdeljebbara, Lalla Hasna; Humam, Munir; Christen, Philippe; Jeannerat, Damien; Vitorge, Bruno; Amzazi, Saaid; Benjouad, Abdelaziz; +2 Authors

doi: 10.1002/hlca.200790041

Withanolides from Withania adpressa

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Abstract

AbstractFrom the leaves of Withania adpressa, a plant endemic to Sahara of Morocco and Algeria, the novel steroidal lactone (22R)‐14α,15α,17β,20β‐tetrahydroxy‐1‐oxowitha‐2,5,24‐trien‐26,22‐olide (= (15S,17S)‐14,15,17,20‐tetrahydroxy‐22,26‐epoxyergosta‐2,5,24‐triene‐1,26‐dione; 1), was isolated, along with three known compounds, withanolides F (2), J (3), and oleanolic acid. Their structures were mainly solved by in‐depth 1D‐ and 2D‐NMR (including ADEQUATE) experiments, as well as by HR‐MS analyses and chemical evidence.

Country

Switzerland

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Keywords

Lactones, Steroids, 540, Withanolides, Withania adpressa

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