Repurposing Drugs for Cognition in Schizophrenia

descriptionPublicationkeyboard_double_arrow_right Article 24 Nov 2016 English Publisher:WileyJournal:Clinical Pharmacology & Therapeutics, volume 101, pages 191-193 (issn: 0009-9236, eissn: 1532-6535,

Copyright policy )

Authors: Y S, Yang; S R, Marder; M F, Green;

doi: 10.1002/cpt.529

pmid: 27706797

Repurposing Drugs for Cognition in Schizophrenia

- Summary
- Subjects
- Metrics

Abstract

Currently approved treatments for schizophrenia only minimally affect the cognitive features of the illness that are the most closely related to disability. Hence, there is now considerable effort to repurpose drugs for schizophrenia, and to seek agents that can improve cognition by targeting receptor systems other than the dopaminergic system. The results of these studies have been mixed thus far; however, this continues to be a high‐priority area of schizophrenia research and an important unmet need.

Related Organizations

University of California, Los Angeles
United States
VA Greater Los Angeles Healthcare System
United States

Keywords

Anti-Inflammatory Agents, Drug Repositioning, Receptors, N-Methyl-D-Aspartate, Cognition, Schizophrenia, Humans, Drug Therapy, Combination, Excitatory Amino Acid Agents, Nicotinic Agonists, Receptors, AMPA, Cognition Disorders, Antipsychotic Agents

Impact byBIP!

	selected citations These citations are derived from selected sources. This is an alternative to the "Influence" indicator, which also reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).	23
	popularity This indicator reflects the "current" impact/attention (the "hype") of an article in the research community at large, based on the underlying citation network.	Top 10%
	influence This indicator reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).	Top 10%
	impulse This indicator reflects the initial momentum of an article directly after its publication, based on the underlying citation network.	Top 10%