Nucleoside‐Based Self‐Assembling Drugs for Localized Drug Delivery
Copyright policy )Nucleoside‐Based Self‐Assembling Drugs for Localized Drug Delivery
AbstractWe have synthesized a range of gelators based on the nucleoside analogues gemcitabine and lamivudine, characterizing representative gels from the series using rheology and transmission electron microscopy. Growth inhibition studies of gemcitabine derivatives confirmed the feasibility of these compounds as novel treatments, indicating the potential of nucleoside‐based gelators for localized drug delivery.
- University of Nottingham United Kingdom
- AstraZeneca (United Kingdom) United Kingdom
gemcitabine, Viscoelastic Substances, gels, Deoxycytidine, Gemcitabine, Drug Delivery Systems, Microscopy, Electron, Transmission, Lamivudine, Cell Line, Tumor, drug delivery, Humans, lamivudine, Drug Screening Assays, Antitumor, Rheology, Gels, nucleosides
gemcitabine, Viscoelastic Substances, gels, Deoxycytidine, Gemcitabine, Drug Delivery Systems, Microscopy, Electron, Transmission, Lamivudine, Cell Line, Tumor, drug delivery, Humans, lamivudine, Drug Screening Assays, Antitumor, Rheology, Gels, nucleosides
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