Microtubule shaft integrity emerges as a crucial determinant of the acetylation pattern

descriptionPublicationkeyboard_double_arrow_right Article 24 Jun 2024 Switzerland, Switzerland English Publisher:WileyJournal:Cytoskeleton, volume 82, pages 55-57 (issn: 1949-3584, eissn: 1949-3592,

Copyright policy )Funded by:SNSF | Kinesin-1 regulated micro...

Authors: Andreu Carbo, Mireia; Egoldt, Cornelia; Aumeier, Charlotte;

doi: 10.1002/cm.21887

pmid: 38923402

pmc: PMC11748361

Microtubule shaft integrity emerges as a crucial determinant of the acetylation pattern

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Abstract

The dynamic nature of microtubules extends beyond the traditional view of these structures merely growing and shortening at their ends. The concept of shaft dynamics introduces a new perspective, focusing away from the ends. Microtubules can be damaged by dissociation of tubulin dimers along the shaft, which can be repaired by incorporating new tubulin dimers, thus restoring structural integrity.

Countries

Switzerland, Switzerland

Related Organizations

University of Geneva
Switzerland
University Hospital of Geneva
Switzerland

Keywords

615, Perspective, 540

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