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Clinical and Translational Allergy
Article . 2025 . Peer-reviewed
License: CC BY
Data sources: Crossref
image/svg+xml art designer at PLoS, modified by Wikipedia users Nina, Beao, JakobVoss, and AnonMoos Open Access logo, converted into svg, designed by PLoS. This version with transparent background. http://commons.wikimedia.org/wiki/File:Open_Access_logo_PLoS_white.svg art designer at PLoS, modified by Wikipedia users Nina, Beao, JakobVoss, and AnonMoos http://www.plos.org/
image/svg+xml art designer at PLoS, modified by Wikipedia users Nina, Beao, JakobVoss, and AnonMoos Open Access logo, converted into svg, designed by PLoS. This version with transparent background. http://commons.wikimedia.org/wiki/File:Open_Access_logo_PLoS_white.svg art designer at PLoS, modified by Wikipedia users Nina, Beao, JakobVoss, and AnonMoos http://www.plos.org/
PubMed Central
Conference object . 2025
License: CC BY
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Feeding the Skin Barrier: The Impact of Macro‐ and Micronutrients on Skin Barrier Function

Authors: Ryczaj, Klaudia; Beken, Burcin; Akdis, Cezmi;

Feeding the Skin Barrier: The Impact of Macro‐ and Micronutrients on Skin Barrier Function

Abstract

ABSTRACT Background Skin is the largest organ of the human body, and acts as a fundamental barrier. Beyond its protective role, it serves as a key immune organ, mediating immune surveillance and regulation. Exposure to environmental factors such as mechanical trauma, detergents, air pollution, and microbial dysbiosis can compromise the skin barrier triggering the release of pro‐inflammatory cytokines that contribute to the pathogenesis of allergic diseases including atopic dermatitis (AD). Nutrition profoundly impacts skin health, influencing cell proliferation, tissue repair, and immune functions. Methods This review aims to explore the relationship between diet and skin barrier function, with a specific focus on AD. Results The evidence on micro‐ and macronutrients, probiotics, and various dietary patterns, highlighting their potential to enhance or impair skin barrier integrity, provides a comprehensive exploration of how diet may serve as a modifiable factor in supporting skin health and preventing allergic diseases. This review also outlines directions for improving future research. Conclusion Diet is an important modifiable factor in preserving skin barrier integrity and may contribute to the prevention and management of AD. However, inconsistent evidence precludes definitive dietary recommendations, highlighting the need for further research.

Keywords

skin, atopic dermatitis, nutrients, dietary patterns, Review Article, diet, 610 Medicine & health

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    This is an alternative to the "Influence" indicator, which also reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
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    popularity
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    Top 10%
    influence
    This indicator reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
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    impulse
    This indicator reflects the initial momentum of an article directly after its publication, based on the underlying citation network.
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selected citations
These citations are derived from selected sources.
This is an alternative to the "Influence" indicator, which also reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
BIP!Citations provided by BIP!
popularity
This indicator reflects the "current" impact/attention (the "hype") of an article in the research community at large, based on the underlying citation network.
BIP!Popularity provided by BIP!
influence
This indicator reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
BIP!Influence provided by BIP!
impulse
This indicator reflects the initial momentum of an article directly after its publication, based on the underlying citation network.
BIP!Impulse provided by BIP!
3
Top 10%
Average
Average
Green
gold