Eugene Braunwald,∗ Dominick Angiolillo,† Eric Bates,‡ Peter B. Berger,§ Deepak Bhatt,|| Christopher P. Cannon,∗ Mark I. Furman,¶ Paul Gurbel,∗∗ Alan D. Michelson,†† Eric Peterson,‡‡ Stephen Wiviott∗ ∗TIMI Study Group, Cardiovascular Division, Brigham and Women’s Hospital, Department of Medicine, Harvard Medical School, Boston, Massachusetts; †Department of Internal Medicine, University of Florida College of Medicine, Jacksonville, Florida; ‡Department of Internal Medicine, University of Michigan, Ann Arbor, Michigan; §Geisinger Center for Health Research, Danville, Pennsylvania; ||Department of Cardiovascular Medicine, Cardiovascular Coordinating Center, Cleveland Clinic, Cleveland, Ohio; ¶Cardiovascular Medicine, South Shore Hospital, South Weymouth, Massachusetts; ∗∗Department of Medicine, Sinai Hospital, Johns Hopkins University School of Medicine, Baltimore, Maryland; ††Center for Platelet Function Studies, Pediatrics, Medicine, and Pathology, University of Massachusetts Medical School, Worcester, Massachusetts; ‡‡Duke University Medical Center, Duke Clinical Research Institute, Durham, North Carolina, USA Address for correspondence: Eugene Braunwald TIMI Study Group Cardiovascular Division Brigham and Women’s Hospital Department of Medicine Harvard Medical School 350 Longwood Avenue Boston, Massachusetts 02115, USA ebraunwald@partners.org