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image/svg+xml Jakob Voss, based on art designer at PLoS, modified by Wikipedia users Nina and Beao Closed Access logo, derived from PLoS Open Access logo. This version with transparent background. http://commons.wikimedia.org/wiki/File:Closed_Access_logo_transparent.svg Jakob Voss, based on art designer at PLoS, modified by Wikipedia users Nina and Beao Canadian Journal of ...arrow_drop_down
image/svg+xml Jakob Voss, based on art designer at PLoS, modified by Wikipedia users Nina and Beao Closed Access logo, derived from PLoS Open Access logo. This version with transparent background. http://commons.wikimedia.org/wiki/File:Closed_Access_logo_transparent.svg Jakob Voss, based on art designer at PLoS, modified by Wikipedia users Nina and Beao
Canadian Journal of Statistics
Article . 2016 . Peer-reviewed
License: Wiley Online Library User Agreement
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image/svg+xml Jakob Voss, based on art designer at PLoS, modified by Wikipedia users Nina and Beao Closed Access logo, derived from PLoS Open Access logo. This version with transparent background. http://commons.wikimedia.org/wiki/File:Closed_Access_logo_transparent.svg Jakob Voss, based on art designer at PLoS, modified by Wikipedia users Nina and Beao
zbMATH Open
Article . 2016
Data sources: zbMATH Open
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Robust prediction of the cumulative incidence function under non‐proportional subdistribution hazards

Robust prediction of the cumulative incidence function under non-proportional subdistribution hazards
Authors: Liu, Qing; Tang, Gong; Costantino, Joseph P.; Chang, Chung-Chou H.;

Robust prediction of the cumulative incidence function under non‐proportional subdistribution hazards

Abstract

AbstractPrediction of a cause‐specific cumulative incidence function (CIF) for data containing competing risks is of primary interest to clinicians when making treatment decisions for patients given their prognostic characteristics. The Fine–Gray regression model is widely used to incorporate multiple prognostic factors, yet it is not applicable when the assumption of proportional subdistribution hazards (PSH) does not hold. In this study we investigate the properties of the partial‐likelihood estimator from the Fine–Gray model under non‐proportionality and propose a robust risk prediction procedure that is not sensitive to the assumption and is more favourable in practice because it bypasses the complicated modelling of time‐varying covariate effects. We evaluate the prediction performance of our procedure in simulations and demonstrate an application in predicting the absolute risk of locoregional recurrence for breast cancer patients, given a set of prognostic factors in which not all of them satisfy the PSH assumption. The Canadian Journal of Statistics 44: 127–141; 2016 © 2016 Statistical Society of Canada

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Keywords

non-proportionality, Brier score, prediction models, Estimation in survival analysis and censored data, inverse probability censoring weight, cumulative incidence function, Applications of statistics to biology and medical sciences; meta analysis, competing risks

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selected citations
These citations are derived from selected sources.
This is an alternative to the "Influence" indicator, which also reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
BIP!Citations provided by BIP!
popularity
This indicator reflects the "current" impact/attention (the "hype") of an article in the research community at large, based on the underlying citation network.
BIP!Popularity provided by BIP!
influence
This indicator reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
BIP!Influence provided by BIP!
impulse
This indicator reflects the initial momentum of an article directly after its publication, based on the underlying citation network.
BIP!Impulse provided by BIP!
4
Average
Average
Average
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