Matrix metalloproteinases
Copyright policy )Matrix metalloproteinases
The matrix metalloproteinases (MMPs) have a role in gastrointestinal malignancy. This role is reviewed, with particular reference to the gelatinase subgroup of enzymes.All relevant papers derived from the Medline and Enbase databases between 1984 and early 1996 were reviewed.There is now strong evidence that MMPs play a major role in tumour invasion and metastasis. The development of MMP inhibitors may lead to important new treatment for the control of malignant disease.
- University of Nottingham United Kingdom
- University of Dundee United Kingdom
Clinical Trials as Topic, Wound Healing, 610, Metalloendopeptidases, Extracellular Matrix, Enzyme Activation, 616, Humans, Neoplasm Invasiveness, Gastrointestinal Neoplasms
Clinical Trials as Topic, Wound Healing, 610, Metalloendopeptidases, Extracellular Matrix, Enzyme Activation, 616, Humans, Neoplasm Invasiveness, Gastrointestinal Neoplasms
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