Inborn errors of GABA metabolism
Copyright policy )Inborn errors of GABA metabolism
AbstractDefects in man in four steps of 4‐aminobutyric acid (GABA) metabolism may interefere with the function of this major inhibitory neurotransmitter. Glutamic acid decarboxylase, 4‐aminobutyric acid aminotransferase, succinic semialdehyde dehydrogenase, and homocarnosinase are closely identified with the brain, but two of these enzymes are expressed in cultured peripheral cells, which may permit novel approaches to the study of the metabolism and regulation of GABA.
- KU Leuven Belgium
- University of California, San Diego United States
- University of California, San Diego United States
- Université Catholique de Louvain Belgium
Dipeptidases, Hydroxybutyrate Dehydrogenase, Glutamate Decarboxylase, 4-Aminobutyrate Transaminase, Humans, Amino Acid Metabolism, Inborn Errors, gamma-Aminobutyric Acid
Dipeptidases, Hydroxybutyrate Dehydrogenase, Glutamate Decarboxylase, 4-Aminobutyrate Transaminase, Humans, Amino Acid Metabolism, Inborn Errors, gamma-Aminobutyric Acid
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