Synthetic Haptens and Monoclonal Antibodies to the Cyanotoxin Anatoxin‐a
Copyright policy )Synthetic Haptens and Monoclonal Antibodies to the Cyanotoxin Anatoxin‐a
AbstractEarly warning systems for monitoring toxic events may benefit from the availability of monoclonal antibodies enabling the sensitive and specific detection of anatoxin‐a, a cyanotoxin involved in numerous cases of animal poisoning resulting from toxic algal blooms in freshwaters. Through the synthesis of three functionalized derivatives of anatoxin‐a, we have succeeded in generating the first‐ever reported immunoreagents (bioconjugates and antibodies) suitable for the development of immunoanalytical approaches aimed at rapid and onsite detection of this harmful cyanotoxin.
Cyanobacteria Toxins, Harmful Algal Bloom, Antibodies, Monoclonal, Enzyme-Linked Immunosorbent Assay, Serum Albumin, Bovine, Stereoisomerism, Animals, Cattle, Haptens, Tropanes
Cyanobacteria Toxins, Harmful Algal Bloom, Antibodies, Monoclonal, Enzyme-Linked Immunosorbent Assay, Serum Albumin, Bovine, Stereoisomerism, Animals, Cattle, Haptens, Tropanes
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