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JAMA
Article . 1980 . Peer-reviewed
Data sources: Crossref
JAMA
Article . 1980
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Extremely Shortened Activated Partial Thromboplastin Times

Authors: Robert R. Belliveau;

Extremely Shortened Activated Partial Thromboplastin Times

Abstract

To the Editor.— The presence of a hypercoagulable state in patients with a shortened activated partial thromboplastin time (APTT) as manifested by the clinical association with an increased incidence of thromboembolic disease has previously been reported by Hume, 1 Gallus et al, 2 Pilgeram, 3 McKenna et al, 4 and McKenna et al. 5 A recent review of patients' clinical records at Southern Nevada Memorial Hospital showed that rather than a history of thrombosis, patients with extremely short (less than 20 s) APTTs actually had a history of spontaneous bleeding. All APTT results that were of a coagulation panel were reviewed during a seven-month period from Jan 1 to July 31, 1979. All APTTs of less than 20 s were selected for evaluation of the clinical chart provided that the patient had a simultaneous normal prothrombin time (less than 13 s), to determine the cause for the hospitalization and the

Keywords

Humans, Hemorrhage, Partial Thromboplastin Time, Blood Coagulation Tests, Adaptation, Physiological

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Found an issue? Give us feedback
citations
This is an alternative to the "Influence" indicator, which also reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
BIP!Citations provided by BIP!
popularity
This indicator reflects the "current" impact/attention (the "hype") of an article in the research community at large, based on the underlying citation network.
BIP!Popularity provided by BIP!
influence
This indicator reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
BIP!Influence provided by BIP!
impulse
This indicator reflects the initial momentum of an article directly after its publication, based on the underlying citation network.
BIP!Impulse provided by BIP!
5
Average
Top 10%
Average
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