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Распространенность сердечно-сосудистых факторов риска у лиц пожилого возраста с «Немыми» инфарктами мозга

Распространенность сердечно-сосудистых факторов риска у лиц пожилого возраста с «Немыми» инфарктами мозга

Abstract

The comparative study of the structure and significance of cardiovascular risk factors for «silent» brain infarctions in 404 patients (202 persons with magnetic resonance signs of «silent» brain infarctions, 202 without them), aged from 62 to 78 years, has shown that arterial hypertension (p < 0.01), abdominal obesity (p < 0.01), smoking (p < 0.05), high blood serum level of creatinin (p < 0.05), and obstructive sleep apnoe (p < 0.05) were risk factors for «silent» brain infarctions in the elderly population of Ukraine. In terms of «silent» brain infarct formation, the most adverse was a simultaneous presence of 3 (p < 0.01) or 4 (p < 0.03) cardiovascular risk factors. The gender factor was significantly associated with arterial hypertension (p < 0.01), abdominal obesity (p < 0.05), and smoking (p < 0.03), but it was not an independent risk factor for «silent» brain infarctions. The study demonstrated a range of significance of specific cardiovascular risk factors for «silent» brain infarctions in the elderly and revealed the importance of further research of the role of a combined impact of risk factors for «silent» brain infarctions.

В сравнительном исследовании по изучению структуры и значимости сердечно-сосудистых факторов риска «немых» инфарктов мозга у 404 лиц (202 с МРТ-признаками «немых» инфарктов мозга, 202 без них) в возрасте от 62 до 78 лет было показано, что артериальная гипертензия (р < 0,01), абдоминальное ожирение (p < 0,01), курение (р < 0,05), повышенный уровень креатинина в плазме крови (р < 0,05) и обструктивное сонное апноэ (р < 0,05) являются факторами риска «немых» инфарктов мозга среди пожилых жителей Украины. Наиболее неблагоприятным с точки зрения развития «немых» инфарктов мозга является одновременное наличие у пациента 3 (р < 0,01) или 4 (р < 0,03) сердечно-сосудистых факторов риска. Гендерный фактор был достоверно связан с артериальной гипертензией (p < 0,01), абдоминальным ожирением (р < 0,05) и курением (р < 0,03), но не являлся независимым фактором риска «немых» инфарктов мозга. Исследование продемонстрировало спектр значимости отдельных сердечно-сосудистых факторов риска «немых» инфарктов мозга у пожилых пациентов и выявило актуальность дальнейшего исследования роли сочетанного действия факторов риска развития «немых» инфарктов мозга.

Keywords

"НЕМЫЕ" ИНФАРКТЫ МОЗГА,"SILENT" BRAIN INFARCTIONS,СЕРДЕЧНО-СОСУДИСТЫЕ ФАКТОРЫ РИСКА,CARDIOVASCULAR RISK FACTORS,ВОЗРАСТ,AGE,РАСПРОСТРАНЕННОСТЬ,PREVALENCE,"НіМі" іНФАРКТИ МОЗКУ,СЕРЦЕВО-СУДИННі ЧИННИКИ РИЗИКУ,ВіК,ПОШИРЕНіСТЬ

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selected citations
These citations are derived from selected sources.
This is an alternative to the "Influence" indicator, which also reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
BIP!Citations provided by BIP!
popularity
This indicator reflects the "current" impact/attention (the "hype") of an article in the research community at large, based on the underlying citation network.
BIP!Popularity provided by BIP!
influence
This indicator reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
BIP!Influence provided by BIP!
impulse
This indicator reflects the initial momentum of an article directly after its publication, based on the underlying citation network.
BIP!Impulse provided by BIP!
0
Average
Average
Average
gold