The purpose of the work is to study the duration and distribution of certain types of activities and rest in the balance of the regime of children with chronic gastroduodenal pathology and to assess the compliance of the duration of the elements of the regime of the day with physiological and hygienic standards. Material and methods. The study covered 135 children with chronic gastroduodenal pathology aged 8–17 years. The main elements of the day regimen were studied by questioning the children and their parents, further assessing the compliance of the duration of the main elements of the regime of the day with physiological and hygienic standards. Results. General conclusion in assessing the compliance of the duration of the main elements of the day regime with physiological and hygienic norms in day 135 children with gastroenterological pathology is a violation of the duration of the main elements of the day regime and the diet of children. The optimal duration of night sleep, which corresponds to age standards, was found in 38.5% of children, the rest of the children has a sleep deficit of varying degrees of severity. Reducing the duration of night sleep is especially pronounced in children aged 15–17 years. Gender differences of the sleep duration was not found in the studied groups except for 16–17 year olds when the average sleep duration in boys was higher by 6.0–8.1% than in girls. In 61.5% of children, the reason for the lack of night sleep is a violation of the time to sleep. The duration of outdoor exposure is insufficient in 40.7% of children. Instead, from 30.4% to 70.4% of children play computer games by conducting a computer screen for more than an hour per day, which exceeds hygiene standards. 57.0% of children need extra time to prepare their homework. According to the results of the study, 81.5% of children eat 3–4 times a day, 18.5% eat only 1–2 times a day. Conclusions. The results of the study have revealed that the duration of the main elements of the daily regime in children with gastroenterological pathology does not meet the physiological and hygienic requirements from 40.7% (duration of stay in the fresh air) to 61.5% (duration of night sleep). Do not follow the diet of 18.5% of children. The normalization of the basic elements of the regime of the day and the diet will promote the strengthening and improvement of children's health.