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European Journal of Epidemiology
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Decline of coronary heart disease mortality is strongly effected by changing patterns of underlying causes of death: an analysis of mortality data from 27 countries of the WHO European region 2000 and 2013

Authors: Susanne Stolpe; Bernd Kowall; Andreas Stang;

Decline of coronary heart disease mortality is strongly effected by changing patterns of underlying causes of death: an analysis of mortality data from 27 countries of the WHO European region 2000 and 2013

Abstract

AbstractMortality rates for coronary heart disease (CHD) experience a longstanding decline, attributed to progress in prevention, diagnostics and therapy. However, CHD mortality rates vary between countries. To estimate whether national patterns of causes of death impact CHD mortality, data from the WHO “European detailed mortality database” for 2000 and 2013 for populations aged ≥ 80 years was analyzed. We extracted mortality rates for total mortality, cardiovascular diseases, neoplasms, dementia and ill-defined causes. We calculated proportions of selected causes of death among all deaths, and proportions of selected cardiovascular causes among cardiovascular deaths. CHD mortality rates were recalculated after re-coding ill-defined causes of death. Association between CHD mortality rates and proportions of CHD deaths was estimated by population-weighted linear regression. National patterns of causes of death were divers. In 2000, CHD was assigned as cause of death in 13–53% of all cardiovascular deaths. Until 2013, this proportion changed between − 65% (Czech Republic) and + 57% (Georgia). Dementia was increasingly assigned as underlying cause of death in Western Europe, but rarely in eastern European countries. Ill-defined causes accounted for between < 1% and 53% of all cardiovascular deaths. CHD mortality rates were closely linked to a countries’ proportion of cardiovascular deaths assigned to CHD (R2 = 0.95 for 2000 and 0.99 for 2013). We show that CHD mortality is considerably influenced by national particularities in certifying death. Changes in CHD mortality rates reflect changes in certifying competing underlying causes of death. This must be accounted for when discussing reasons for the CHD mortality decline.

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Keywords

Adult, Male, Coronary heart disease mortality, Time Factors, very elderly, Medizin, Western Europe, Coronary Disease, Eastern Europe, mortality rate, World Health Organization, survival analysis, cause of death, Mortality registry data, cardiovascular mortality, time factor, Cause of Death, middle aged, Humans, atrial fibrillation, Registries, Mortality, Georgia (republic), Causes of death, Aged, Czech Republic, Aged, 80 and over, Middle Aged, ischemic heart disease, Survival Analysis, Coronary Disease/epidemiology [MeSH] ; Mortality registry data ; Female [MeSH] ; Aged, 80 and over [MeSH] ; Aged [MeSH] ; Coronary heart disease mortality ; Adult [MeSH] ; Mortality/trends [MeSH] ; Humans [MeSH] ; Survival Analysis [MeSH] ; Middle Aged [MeSH] ; Time Factors [MeSH] ; Coronary Disease/diagnosis [MeSH] ; Cause of Death/trends [MeSH] ; Mortality ; Male [MeSH] ; Causality [MeSH] ; Coronary Disease/mortality [MeSH] ; Dementia/epidemiology [MeSH] ; Causes of death ; Registries [MeSH] ; Mortality patterns, Europe, Causality, female, Mortality patterns, Female, Dementia, Dewey Decimal Classification::600 | Technik::610 | Medizin, Gesundheit, coronary artery disease, dementia, heart atrium flutter

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selected citations
These citations are derived from selected sources.
This is an alternative to the "Influence" indicator, which also reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
BIP!Citations provided by BIP!
popularity
This indicator reflects the "current" impact/attention (the "hype") of an article in the research community at large, based on the underlying citation network.
BIP!Popularity provided by BIP!
influence
This indicator reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
BIP!Influence provided by BIP!
impulse
This indicator reflects the initial momentum of an article directly after its publication, based on the underlying citation network.
BIP!Impulse provided by BIP!
29
Top 10%
Top 10%
Top 10%
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