The analysis of national and foreign scientific publications for scientific approaches, according to the method of multi-criteria assessment. As a result of the analysis, the relevance of the topic was proved and the purpose of the work was determined. Since the indicators of harmful factors affecting human health are of a different nature, that is, their indicators are different, and they have different assessment scales, and there is no single methodology for their assessment, it would be advisable to apply a system of dependencies between different-sized indicators of harmful factors in production and their estimates on a dimensionless scale, which would take into account the importance of a harmful factor for the human body, regardless of the type of industrial premises. The article proposes to assess the indicators of harmful factors, to apply dependencies that take into account the maximum, minimum and optimal values and the shape parameter, changing which you can get various estimates on a dimensionless scale. Two groups of indicators of harmful factors were determined and built for each group of dependence, which made it possible to unify the system of dependencies for assessing indicators of harmful factors. To determine the shape parameter, it is proposed to apply the theory of expert assessments, where decision making is understood as choosing an alternative from a set based on the analysis of factors or criteria. Applying the proposed coefficients as a parameter of the form of the dependency system, in each individual case, depending on the indicator of the harmful factor, it is possible to recommend strict or weaker requirements for indicators. Hazardous and harmful factors in a sausage shop at a meat processing plant have been analyzed and their permissible norms have been determined in accordance with regulatory documents. The approbation of the methodology for multi-criteria assessment of indicators of harmful factors was proposed. The assessment of indicators of harmful factors is graphically constructed. The scales are marked with the maximum and minimum allowable values of indicators of harmful factors. A generalized indicator of harmful factors has been determined for the basis for making a decision on further actions to improve working conditions.