This paper delves into the transformative role of the Fourth Industrial Revolution (4IR) technologies—Artificial Intelligence (AI), the Internet of Things (IoT), Robotics, and Blockchain—in reshaping strategic intelligence and dynamic capabilities in businesses. It presents an in-depth analysis of how these technologies enhance strategic decision-making, predictive analytics, and operational agility, thereby contributing to a sustainable competitive advantage in rapidly evolving markets. The paper also explores the synergistic effects of integrating these technologies and the resulting challenges and opportunities, including cybersecurity risks, workforce displacement, and ethical considerations. Furthermore, it proposes a comprehensive framework that integrates technology adoption with organizational strategy, emphasizing continuous learning, sustainability, and ethical practices. This study concludes by discussing the implications for practitioners and policymakers and suggesting directions for future research, particularly in understanding long-term impacts, cross-industry applications, and societal implications of 4IR technologies. This paper aims to provide valuable insights for businesses and policymakers navigating the complexities of the 4IR era.