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image/svg+xml Jakob Voss, based on art designer at PLoS, modified by Wikipedia users Nina and Beao Closed Access logo, derived from PLoS Open Access logo. This version with transparent background. http://commons.wikimedia.org/wiki/File:Closed_Access_logo_transparent.svg Jakob Voss, based on art designer at PLoS, modified by Wikipedia users Nina and Beao Biological Psychiatr...arrow_drop_down
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Biological Psychiatry
Article . 2024 . Peer-reviewed
License: Elsevier TDM
Data sources: Crossref
Biological Psychiatry
Article . 2024
Data sources: u:cris
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Accelerated Theta Burst Stimulation: Safety, Efficacy, and Future Advancements

Safety, Efficacy, and Future Advancements
Authors: Eleanor Cole; Sean J. O’Sullivan; Martin Tik; Nolan R. Williams;

Accelerated Theta Burst Stimulation: Safety, Efficacy, and Future Advancements

Abstract

Theta burst stimulation (TBS) is a noninvasive brain stimulation technique that can be used to modulate neural networks underlying psychiatric and neurological disorders. TBS can be delivered intermittently or continuously. The conventional intermittent TBS protocol is approved by the U.S. Food and Drug Administration to treat otherwise treatment-resistant depression, but the 6-week duration limits the applicability of this therapy. Accelerated TBS protocols present an opportunity to deliver higher pulse doses in shorter periods of time, thus resulting in faster and potentially more clinically effective treatment. However, the acceleration of TBS delivery raises questions regarding the relative safety, efficacy, and durability compared with conventional TBS protocols. In this review paper, we present the data from accelerated TBS trials to date that support the safety and effectiveness of accelerated protocols while acknowledging the need for more durability data. We discuss the stimulation parameters that seem to be important for the efficacy of accelerated TBS protocols and possible avenues for further optimization.

Keywords

MDD, Depressive Disorder, Theta Rhythm/physiology, Efficacy, Brain, Review, Major depressive disorder, Transcranial Magnetic Stimulation, Transcranial Magnetic Stimulation/adverse effects, Depressive Disorder, Treatment-Resistant, aTBS, Treatment Outcome, Brain stimulation, Theta burst stimulation, 302065 Psychiatrie, TBS, Humans, Accelerated theta burst stimulation, Theta Rhythm, 302065 Clinical psychiatry, Treatment-Resistant/therapy

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selected citations
These citations are derived from selected sources.
This is an alternative to the "Influence" indicator, which also reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
BIP!Citations provided by BIP!
popularity
This indicator reflects the "current" impact/attention (the "hype") of an article in the research community at large, based on the underlying citation network.
BIP!Popularity provided by BIP!
influence
This indicator reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
BIP!Influence provided by BIP!
impulse
This indicator reflects the initial momentum of an article directly after its publication, based on the underlying citation network.
BIP!Impulse provided by BIP!
47
Top 1%
Top 10%
Top 1%
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