This paper presents the general strategies of the post-war anomie’s overcoming in the fields of social interactions and business. The main purpose of the research is to study developmental features of the anomic behavior, and possible behavioral pathologies of people in business environment that can occur in post-war society. Investigation of this topic in the paper is carried out in the following logical sequence: at the initial stage of the research, an analysis of the main stages of the phenomenon of anomie in human life was carried out. Based on the analysis results, it is substantiated that a number of socio-psychological problems arise when social interactions are changed, and business environment is developed rapidly. This tendency is more visible in a post-war society. The aim of the research is the systematization of methodological approaches for implementations the psychological aid and work in mental correction and rehabilitation among people with anomic behavior, to prevent the deepening of the negative symptoms endangering emotional state and possible behavioral pathologies do not become deeper and endanger the whole society. The paper presents the results of an empirical analysis, which showed that the person with anomic behavior or marginal person falls into the psychological shock, which is characterized by the following aspects such as tensions caused by efforts to achieve the necessary psychological adaptation, emotion of loss and depreciation (friends, status, property and profession), feeling of rejection, violation of roles, role expectations, values, self-identification of emotions, existence of an unexpected alarm, hatred, disgust as a result of the realization of cultural differences and, finally, feeling of non-completeness due to failure to adapt to the new business environment. Based on the results of the study of various societies during the post-war period, the article identified strategies for overcoming social anomie in the spheres of social interactions and business. The main strategy types include unification strategy, professional specific orientations, disintegration of vital activities, retreat strategy, adventurism, anti-sublimation (humiliation behavior) and innovative strategy. The identification of strategic priorities for overcoming anomie, which are of practical meaning for productive business sphere management, should serve as the perspective directions for further research.