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Basic & Clinical Pharmacology & Toxicology
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Development of a quick guide for assessment of the most frequently used renal risk medication in Danish hospitals and primary care

Authors: Lene Vestergaard Ravn‐Nielsen; Trine Rune Høgh Andersen; Charlotte Olesen; Ulla Hedegaard; Faruk Coric; Lisa Greve Routhe; Joo Hanne Poulsen Revell; +3 Authors

Development of a quick guide for assessment of the most frequently used renal risk medication in Danish hospitals and primary care

Abstract

AbstractDue to changes in pharmacokinetics and pharmacodynamics, patients with impaired renal function suffer an increased risk of suboptimal and potentially harmful medication treatment. This necessitates careful consideration of medications affected by impaired renal function when performing medication reviews. The aim of this study was to develop a quick guide (a list of recommendations) for assessing renal risk medications in medication reviews led by hospital pharmacists. The list was based on the 100 most frequently used medications in Danish hospitals and primary care. After combining the 200 records, 29 duplicates were excluded resulting in a pool of 171 medications. Assessment by two clinical pharmacists led to the exclusion of 121 medications. Of the remaining 50 medications, seven were discussed among the two pharmacists, and two of these were also in the research group to reach a consensus. The renal risk quick guide comprised 50 medications. The most prevalent medications on the list were from Anatomical Therapeutic Chemical Classification System (ATC)‐group N, C and L. Recommendations from two databases were included in the quick guide in order to provide clinical pharmacists with existing, updated evidence on medication use in impaired renal function. The next step is to test the feasibility of the quick guide in daily practice when performing medication reviews.

Keywords

Male, Drug-Related Side Effects and Adverse Reactions, Denmark, Kidney/drug effects, Pharmacy Service, Pharmacists, Kidney, Risk Assessment, Hospital/organization & administration, risk assessment quick guide, impaired renal function, Humans, Pharmacists/organization & administration, Renal Insufficiency, Aged, Primary Health Care, Renal Insufficiency/chemically induced, medication optimisation, Hospitals, Drug-Related Side Effects and Adverse Reactions/prevention & control, Practice Guidelines as Topic, renal risk medication, Female, clinical pharmacology, Pharmacy Service, Hospital

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selected citations
These citations are derived from selected sources.
This is an alternative to the "Influence" indicator, which also reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
BIP!Citations provided by BIP!
popularity
This indicator reflects the "current" impact/attention (the "hype") of an article in the research community at large, based on the underlying citation network.
BIP!Popularity provided by BIP!
influence
This indicator reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
BIP!Influence provided by BIP!
impulse
This indicator reflects the initial momentum of an article directly after its publication, based on the underlying citation network.
BIP!Impulse provided by BIP!
2
Top 10%
Average
Average
Green
hybrid