Powered by OpenAIRE graph
Found an issue? Give us feedback
image/svg+xml art designer at PLoS, modified by Wikipedia users Nina, Beao, JakobVoss, and AnonMoos Open Access logo, converted into svg, designed by PLoS. This version with transparent background. http://commons.wikimedia.org/wiki/File:Open_Access_logo_PLoS_white.svg art designer at PLoS, modified by Wikipedia users Nina, Beao, JakobVoss, and AnonMoos http://www.plos.org/ Вестник медицинского...arrow_drop_down
image/svg+xml art designer at PLoS, modified by Wikipedia users Nina, Beao, JakobVoss, and AnonMoos Open Access logo, converted into svg, designed by PLoS. This version with transparent background. http://commons.wikimedia.org/wiki/File:Open_Access_logo_PLoS_white.svg art designer at PLoS, modified by Wikipedia users Nina, Beao, JakobVoss, and AnonMoos http://www.plos.org/
image/svg+xml art designer at PLoS, modified by Wikipedia users Nina, Beao, JakobVoss, and AnonMoos Open Access logo, converted into svg, designed by PLoS. This version with transparent background. http://commons.wikimedia.org/wiki/File:Open_Access_logo_PLoS_white.svg art designer at PLoS, modified by Wikipedia users Nina, Beao, JakobVoss, and AnonMoos http://www.plos.org/
versions View all 2 versions
addClaim

This Research product is the result of merged Research products in OpenAIRE.

You have already added 0 works in your ORCID record related to the merged Research product.

Clusters of patients with chronic heart failure based on the analysis of body composition parameters and palliative status

Authors: V. I. Shevtsova; A. A. Pashkova; A. N. Shevtsov; Yu. V. Burenkov;

Clusters of patients with chronic heart failure based on the analysis of body composition parameters and palliative status

Abstract

The aim of the study: to divide a heterogeneous group of patients with chronic heart failure, taking into account the parameters of body composition and severity of painful symptoms. Object and methods. The study involved 298 patients with CHF. The body composition was assessed: the presence of sarcopenia and obesity (with the calculation of the muscle mass index), functional class, left ventricular ejection fraction, markers galectin-3, hsCRP sodium uretic peptide, Bartel index. A 10-point Edmont scale was used to assess the severity of painful symptoms. A two-stage cluster analysis was performed. Results. Three clusters were identified in the patient structure: the share of the first in the overall structure was 23.2%, the second – 61.1%, the third – 15.8%. It was determined that the first cluster includes patients with sarcopenic obesity. They are characterized by the maximum galectin level and ejection fraction in the sample. They have low walking speed, dynamometry, NТ-proBNP. The intermediate position is occupied by patients of the second cluster (patients with isolated body composition disorder or without it). They are characterized by high walking speed, dynamometry indicators, 6-minute walking test value, Barthel index. Patients of the third cluster are people with low body weight and sarcopenia. They have the maximum Sarcopenia Fast questionnaire level with low walking speed, T6W value, dynamometry indicators and significantly reduced ejection fractions and a high NТ-proBNP level. Patients of the first cluster have the most pronounced pain and fatigue with the lowest level of depression. In patients of the second cluster, pain, fatigue, drowsiness, nausea, shortness of breath, anxiety, and well-being are expressed much less than in patients of the other clusters. And patients of the third group have the highest level of drowsiness, nausea, appetite disorders, shortness of breath, depression, anxiety, and deterioration of well-being. Conclusions. The structure and severity of distressing symptoms varies depending on the cluster and, accordingly, the patient's body composition, which can be used in constructing algorithms for providing palliative care to patients with CHF.

Related Organizations
Keywords

Medicine (General), prognosis [d011379], comorbidity [d015897], metabolic disorders [d008659], chronic heart failure [d006333], body composition [d001823], bioimpedance analysis [d019160], lean body mass [d050152], palliative status [d010166], risk stratification [d018570], quality of life [d011788], R5-920, functional status [d005260], personalized medicine [d057285], body fat mass [d050153], cluster analysis [d002982]

  • BIP!
    Impact byBIP!
    selected citations
    These citations are derived from selected sources.
    This is an alternative to the "Influence" indicator, which also reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
    0
    popularity
    This indicator reflects the "current" impact/attention (the "hype") of an article in the research community at large, based on the underlying citation network.
    Average
    influence
    This indicator reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
    Average
    impulse
    This indicator reflects the initial momentum of an article directly after its publication, based on the underlying citation network.
    Average
Powered by OpenAIRE graph
Found an issue? Give us feedback
selected citations
These citations are derived from selected sources.
This is an alternative to the "Influence" indicator, which also reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
BIP!Citations provided by BIP!
popularity
This indicator reflects the "current" impact/attention (the "hype") of an article in the research community at large, based on the underlying citation network.
BIP!Popularity provided by BIP!
influence
This indicator reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
BIP!Influence provided by BIP!
impulse
This indicator reflects the initial momentum of an article directly after its publication, based on the underlying citation network.
BIP!Impulse provided by BIP!
0
Average
Average
Average
gold