PROSPECTS FOR CYTOPROTECTORS USE IN THE ELDERLY PATIENTS THROUGH THE EXAMPLE OF CALCIFIED AORTIC STENOSIS AND ISCHEMIC HEART DISEASE

descriptionPublicationkeyboard_double_arrow_right Article 01 Jan 2015Publisher:Silicea - PoligrafJournal:Rational Pharmacotherapy in Cardiology, volume 11, pages 431-437 (issn: 1819-6446, eissn: 2225-3653,

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Authors: N. Yu. Karpova; M. A. Rashid; N. A. Shostak; I. V. Pogonchenkova; T. V. Kazakova;

doi: 10.20996/1819-6446-2015-11-4-431-437

PROSPECTS FOR CYTOPROTECTORS USE IN THE ELDERLY PATIENTS THROUGH THE EXAMPLE OF CALCIFIED AORTIC STENOSIS AND ISCHEMIC HEART DISEASE

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Abstract

Issues of pathogenesis of the calcified aortic stenosis and ischemic heart disease in the elderly are considered. The relevance of early detection of angina, syncope, and dyspnea in view of their non-specific and subclinical course for early detection of heart disease is specified. Current scientific views on the myocardial bioenergy and its role in the genesis of chronic heart failure are presented. Particular attention is paid to the place of cytoprotectors, especially trimetazidine, in the management of patients with cardiac N.Yu. Karpova1diseases.

Related Organizations

Moscow Aviation Institute
Russian Federation
Moscow City Hospital No 29
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Pirogov Russian National Research Medical University
Russian Federation
Moscow Power Engineering Institute
Russian Federation

Keywords

trimetazidine, биоэнергетика сердца, ишемическая болезнь сердца, RM1-950, кальцинированный аортальный стеноз, ischemic heart disease, триметазидин, цитопротекторы, heart bioenergy, RC666-701, Diseases of the circulatory (Cardiovascular) system, Therapeutics. Pharmacology, cytoprotectors, calcified aortic stenosis

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