Abstract Aim To identify barriers and facilitators impacting the implementation of a comprehensive transfer program aimed at parents of adolescents with chronic illness in clinical practice. Design A real‐time, qualitative process evaluation. Methods Individual interviews were conducted with 10 nurses and seven physicians from paediatric and adult outpatient clinics: Nephrology, hepatology, neurology, and rheumatology. Data were analysed through the lens of normalization process theory. Results Themes were framed within the theory's four components. (1) Coherence : Healthcare professionals' views on their core tasks and on the parents' role influenced their perception of the program. (2) Cognitive participation : A named key worker, autonomy, and collaboration impacted healthcare professionals' involvement in the program. (3) Collective action : Department prioritization and understanding of the program's aim were key factors in its successful delivery. (4) Reflective monitoring : Participants experienced that the program helped parents during transfer but questioned if the program was needed by all families. Conclusion We identified three barriers: Healthcare professionals' lack of understanding of the parental role during transfer, top‐down decisions among nurses, and physicians' uncertainty about their role in joint consultations. Facilitators: Healthcare professionals' understanding of the program's purpose and expected effect, the nurses' significant role as named keyworkers, and good collaboration across paediatric and adult departments. Implications for the Profession and/or Patient Care Implementation strategies should be developed before implementing a transfer program in clinical practice. Impact Implementing a parental transfer program in clinical practice can be challenging. Therefore, for successful implementation, it is crucial to identify barriers and facilitators. Barriers and facilitators exist at the personal, professional, and organizational levels, and it is important to understand them. The results of this qualitative study could support the implementation of transfer programs in other settings. Reporting Method Consolidated criteria for reporting qualitative studies (COREQ). Patient or Public Contribution No patient or public contribution. What does this paper contribute to the wider global clinical community? Nurses' and physicians' experiences of ownership of the transfer program is essential for successful implementation. Clinics should appoint a named keyworker, preferably a nurse, as the driving force during the implementation of a transfer program. Nurses and physicians should receive training about the purpose, justification, and expected effect of a transfer program before implementation.