Circadian control of the immune system
Copyright policy )Circadian control of the immune system
Circadian rhythms, which have long been known to play crucial roles in physiology, are emerging as important regulators of specific immune functions. Circadian oscillations of immune mediators coincide with the activity of the immune system, possibly allowing the host to anticipate and handle microbial threats more efficiently. These oscillations may also help to promote tissue recovery and the clearance of potentially harmful cellular elements from the circulation. This Review summarizes the current knowledge of circadian rhythms in the immune system and provides an outlook on potential future implications.
- University of Geneva Switzerland
- Yeshiva University United States
- Albert Einstein College of Medicine United States
Transcription, Genetic, Inflammation/immunology/physiopathology, Physiological/physiology, Mammals/immunology/physiology, Adaptive Immunity, Chronobiology Disorders, Feedback, Circadian Rhythm Signaling Peptides and Proteins/genetics/physiology, Chronobiology Disorders/immunology, Mice, Models, Circadian Rhythm/immunology, Animals, Humans, Hormones/physiology, Adaptive Immunity/physiology, Feedback, Physiological, Inflammation, Mammals, Gene Expression Regulation/physiology, Circadian Rhythm Signaling Peptides and Proteins, Drug Chronotherapy, Immunity, Models, Immunological, Genetic/physiology, Immune System/physiology, Hormones, Blood Cell Count, Circadian Rhythm, Immunity, Humoral, Immunological, Gene Expression Regulation, Immune System, Humoral/physiology, Disease Susceptibility, Transcription
Transcription, Genetic, Inflammation/immunology/physiopathology, Physiological/physiology, Mammals/immunology/physiology, Adaptive Immunity, Chronobiology Disorders, Feedback, Circadian Rhythm Signaling Peptides and Proteins/genetics/physiology, Chronobiology Disorders/immunology, Mice, Models, Circadian Rhythm/immunology, Animals, Humans, Hormones/physiology, Adaptive Immunity/physiology, Feedback, Physiological, Inflammation, Mammals, Gene Expression Regulation/physiology, Circadian Rhythm Signaling Peptides and Proteins, Drug Chronotherapy, Immunity, Models, Immunological, Genetic/physiology, Immune System/physiology, Hormones, Blood Cell Count, Circadian Rhythm, Immunity, Humoral, Immunological, Gene Expression Regulation, Immune System, Humoral/physiology, Disease Susceptibility, Transcription
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