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Revista do Colégio Brasileiro de Cirurgiões
Article . 2015 . Peer-reviewed
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Use of surgical mesh of different compositions in the correction of the abdominal wall defect in rats

Authors: Isa, Ana Cristina; Matias, Jorge Eduardo Fouto; Yamamoto, Celia Toshie; Isa, Rosana Hapsi; Campos, Antônio Carlos Ligocki; Coelho, Júlio Cezar Uili;

Use of surgical mesh of different compositions in the correction of the abdominal wall defect in rats

Abstract

Objective: To analyze the performance of two surgical meshes of different compositions during the defect healing process of the abdominal wall of rats. Methods: thirty-three adult Wistar rats were anesthetized and subjected to removal of an area of 1.5 cm x 2 cm of the anterior abdominal wall, except for the skin; 17 animals had the defect corrected by edge-to-edge surgical suture of a mesh made of polypropylene + poliglecaprone (Group U - UltraproTM); 16 animals had the defect corrected with a surgical mesh made of polypropylene + polidioxanone + cellulose (Group P - ProceedTM). Each group was divided into two subgroups, according to the euthanasia moment (seven days or 28 days after the operation). Parameters analyzed were macroscopic (adherence), microscopic (quantification of mature and immature collagen) and tensiometric (maximum tension and maximum rupture strength). Results : there was an increase in collagen type I in the ProceedTM group from seven to 28 days, p = 0.047. Also, there was an increase in the rupture tension on both groups when comparing the two periods. There was a lower rupture tension and tissue deformity with ProceedTM mesh in seven days, becoming equal at day 28. Conclusion : the meshes retain similarities in the final result and more studies with larger numbers of animals must be carried for better assessment.

Related Organizations
Keywords

Telas Cirúrgicas, RD1-811, Abdominal Wall, Parede abdominal/cirurgia, Tissue Adhesions, Biocompatible Materials, Surgical Mesh, Polypropylenes, Hernia, Abdominal, Rats, Abdominal Wall/surgery, Animals, Surgery, Rats, Wistar, Hérnia Abdominal, Aderências Teciduais

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selected citations
These citations are derived from selected sources.
This is an alternative to the "Influence" indicator, which also reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
BIP!Citations provided by BIP!
popularity
This indicator reflects the "current" impact/attention (the "hype") of an article in the research community at large, based on the underlying citation network.
BIP!Popularity provided by BIP!
influence
This indicator reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
BIP!Influence provided by BIP!
impulse
This indicator reflects the initial momentum of an article directly after its publication, based on the underlying citation network.
BIP!Impulse provided by BIP!
4
Average
Average
Average
Green
gold