Extensively drug-resistant Haemophilus influenzae isolated in Geneva, Switzerland
Copyright policy )Extensively drug-resistant Haemophilus influenzae isolated in Geneva, Switzerland
Abstract The emergence of multi-drug resistant (MDR) and even extensively drug-resistant (XDR) strains among H. influenzae was observed in some Asian countries. Herein, we reported the first XDR H. influenzae isolated in Geneva, Switzerland. This strain was isolated in a good-quality sputum sample from a 63 year-old male patient. There was no respiratory infection diagnosed at that time. The strain was non-typeable and pan-β-lactam resistant. According to whole genome sequencing analysis it belongs to sequence type 159 and the ST-107 clonal complex. It was classified into group III + regarding the amino acid substitutions identified in the transpeptidase domain of PBP3.
- University of Geneva Switzerland
- University Hospital of Geneva Switzerland
Male, Ceftriaxone resistance, Haemophilus influenzae / genetics, Haemophilus Infections, Whole Genome Sequencing, Brief Report, Sputum, Haemophilus influenzae / classification, Extensively drug resistant, Microbial Sensitivity Tests, Middle Aged, Anti-Bacterial Agents / pharmacology, Haemophilus influenzae, Haemophilus influenzae / drug effects, Anti-Bacterial Agents, Haemophilus Infections / microbiology, Drug Resistance, Multiple, Bacterial, 616, Sputum / microbiology, Humans, Haemophilus influenzae / isolation & purification, Penicillin-binding protein 3 amino acid substitutions, Switzerland
Male, Ceftriaxone resistance, Haemophilus influenzae / genetics, Haemophilus Infections, Whole Genome Sequencing, Brief Report, Sputum, Haemophilus influenzae / classification, Extensively drug resistant, Microbial Sensitivity Tests, Middle Aged, Anti-Bacterial Agents / pharmacology, Haemophilus influenzae, Haemophilus influenzae / drug effects, Anti-Bacterial Agents, Haemophilus Infections / microbiology, Drug Resistance, Multiple, Bacterial, 616, Sputum / microbiology, Humans, Haemophilus influenzae / isolation & purification, Penicillin-binding protein 3 amino acid substitutions, Switzerland
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