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Neurology
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Neurology
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Article . 2002 . Peer-reviewed
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Article . 2003 . Peer-reviewed
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Predictors of effective bilateral subthalamic nucleus stimulation for PD

descriptionPublicationkeyboard_double_arrow_right Article 24 Sep 2002 English Publisher:Ovid Technologies (Wolters Kluwer Health)Journal:Neurology, volume 59, pages 932-934 (issn: 0028-3878, eissn: 1526-632X, Copyright policy )
Authors: Charles, David; Van Blercom, Nadege; Krack, Paul; Lee, Seulki; Xie, Jing; Besson, Gérard; Benabid, Alim-Louis; +1 Authors

doi: 10.1212/wnl.59.6.932 , 10.1212/wnl.60.5.886

pmid: 12297584

Predictors of effective bilateral subthalamic nucleus stimulation for PD

Abstract

To identify factors predictive of effective bilateral subthalamic nucleus (STN) stimulation for PD with severe motor complications, pre- and postoperative Unified PD Rating Scale (UPDRS) scores were analyzed in a series of 54 patients who received bilateral STN stimulation. Younger age and levodopa responsiveness predict a favorable response to bilateral STN stimulation. For individual PD symptoms, those that improve with a suprathreshold dose levodopa challenge are likely to improve with stimulation.

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Keywords

Adult, Male, Parkinson Disease/drug therapy/physiopathology/*surgery, Levodopa/therapeutic use, Age Factors, Electric Stimulation Therapy, Parkinson Disease, Middle Aged, Statistics, Nonparametric, Levodopa, Subthalamic Nucleus, Subthalamic Nucleus/*surgery, Multivariate Analysis, Preoperative Care, Preoperative Care/statistics & numerical data, Humans, Regression Analysis, Female, Electric Stimulation Therapy/methods/*statistics & numerical data, Aged

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    selected citations
    These citations are derived from selected sources.
    This is an alternative to the "Influence" indicator, which also reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
    		 261
    popularity
    This indicator reflects the "current" impact/attention (the "hype") of an article in the research community at large, based on the underlying citation network.
    		 Top 1%
    influence
    This indicator reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
    		 Top 1%
    impulse
    This indicator reflects the initial momentum of an article directly after its publication, based on the underlying citation network.
    		 Top 10%
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selected citations
These citations are derived from selected sources.
This is an alternative to the "Influence" indicator, which also reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
BIP!Citations provided by BIP!
popularity
This indicator reflects the "current" impact/attention (the "hype") of an article in the research community at large, based on the underlying citation network.
BIP!Popularity provided by BIP!
influence
This indicator reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
BIP!Influence provided by BIP!
impulse
This indicator reflects the initial momentum of an article directly after its publication, based on the underlying citation network.
BIP!Impulse provided by BIP!
261
Top 1%
Top 1%
Top 10%
Green
bronze