The level of the soluble molecule of adhesion of vascular cells-1 and L-selectin in patients with antiphospholipid syndrome: a relationship with the disease activity, endothelial dysfunction and atherosclerosis
Copyright policy )The level of the soluble molecule of adhesion of vascular cells-1 and L-selectin in patients with antiphospholipid syndrome: a relationship with the disease activity, endothelial dysfunction and atherosclerosis
A significant increase of the indices of the molecule of adhesion of vascular cells-1 (sVCAM-1) and Lselectin was demonstrated in the course of the research in the blood of patients with antiphospholipid syndrome as compared with healthy persons. The levels of the substances under study were associated with the markers of the activity of an inflammatory process (ESR, TNF-α, IL-1, CRP), disturbances of the lipid metabolism, the presence of antiphospholipid antibodies and concomitant arterial hypertension, however, they practically did not depend on the age, gender, the duration of the disease, tobacco smoking, obesity and hypodynamia. Close correlations have also been established between an elevated concentration of sVCAM-1 and L-selectin and structural functional changes of the vascular endothelium, enabling to regard them to be circulating markers of an early development of atherosclerosis in patients with antiphospholipid syndrome.
vascular cell adhesion molecule-1 (sVCAM), дислипидемия, структурно-функциональные изменения эндотелия сосудов, dyslipidemia, antiphospholipid antibodies, антифосфоліпідний синдром, структурно-функціональні зміни ендотелію судин, structural and functional changes in vascular endothelium, молекула адгезії судинних клітин-1 (sVCAM-1), дисліпідемія, антифосфолипидные антитела, антифосфоліпідні антитіла, активність захворювання, L-селектин, антифосфолипидный синдром, активность заболевания, antiphospholipid syndrome, L-selectin, disease activity, молекула адгезии сосудистых клеток-1
vascular cell adhesion molecule-1 (sVCAM), дислипидемия, структурно-функциональные изменения эндотелия сосудов, dyslipidemia, antiphospholipid antibodies, антифосфоліпідний синдром, структурно-функціональні зміни ендотелію судин, structural and functional changes in vascular endothelium, молекула адгезії судинних клітин-1 (sVCAM-1), дисліпідемія, антифосфолипидные антитела, антифосфоліпідні антитіла, активність захворювання, L-селектин, антифосфолипидный синдром, активность заболевания, antiphospholipid syndrome, L-selectin, disease activity, молекула адгезии сосудистых клеток-1
selected citations These citations are derived from selected sources.This is an alternative to the "Influence" indicator, which also reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).0 popularity This indicator reflects the "current" impact/attention (the "hype") of an article in the research community at large, based on the underlying citation network.Average influence This indicator reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).Average impulse This indicator reflects the initial momentum of an article directly after its publication, based on the underlying citation network.Average
Citations provided by BIP!Popularity provided by BIP!